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Index > Protein center > Snrnp70(Gene name) > Mouse
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  • Snrnp70 (Gene name),
  • U1 small nuclear ribonucleoprotein 70 kDa (Protein name ),  RU17_MOUSE from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Vaild Sequence
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  • Gene name:
    Snrnp70(Snrp70);
    Protein name:
    U1 small nuclear ribonucleoprotein 70 kDa(U1 snRNP 70 kDa;U1-70K;snRNP70);
    Alternative:

    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    Found in a pre-mRNA splicing complex with SFRS4, SFRS5, SNRNP70, SNRPA1, SRRM1 and SRRM2. Found in a pre-mRNA exonic splicing enhancer (ESE) complex with SNRNP70, SNRPA1, SRRM1 and TRA2B/SFRS10. Interacts with dephosphorylated SFRS13A and SFPQ. Interacts with NUDT21/CPSF5, CPSF6, SCAF11 and ZRANB2.
    Function:
    Mediates the splicing of pre-mRNA by binding to the loop I region of U1-snRNA. The truncated isoform cannot bind U1-snRNA.
    Subcellular Location:
    Nucleus
    Protein Attributes:
    Sequence length:
    448
    Sequence:
    50:
    MTQFLPPNLL | ALFAPRDPIP | YLPPLEKLPH | EKHHNQPYCG | IAPYIREFED | 
    100:
    PRDAPPPTRA | ETREERMERK | RREKIERRQQ | EVETELKMWD | PHNDPNAQGD | 
    150:
    AFKTLFVARV | NYDTTESKLR | REFEVYGPIK | RIHMVYSKRS | GKPRGYAFIE | 
    200:
    YEHERDMHSA | YKHADGKKID | GRRVLVDVER | GRTVKGWRPR | RLGGGLGGTR | 
    250:
    RGGADVNIRH | SGRDDTSRYD | ERPGPSPLPH | RDRDRDRERE | RRERSRERDK | 
    300:
    ERERRRSRSR | DRRRRSRSRD | KDERRRSRER | SKDKDRDRKR | RSSRSRERAR | 
    350:
    RERERKEELR | GGGGGGGGGS | GGGGGGDMAE | PSEAGDGAPD | DGPPGELGPE | 
    400:
    GPDGPEEKGR | DRDRERRRSH | RSERERRRDR | DRDRDREHKR | GERGSERGRD | 
    448:
    EARGGGGSGQ | DNGLEGLGSD | GRDMYMEAEG | GDGYMAPENG | YLMEAAPE
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
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    Related Databases
    SMR:
    KEGG:
    UniGene:
    String:
    Pfam:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse U1 snRNP 70 kDa
    Cat.:
    E13128m
    Price:
    Please sign in first.
    MSDS:
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    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Mouse U1 snRNP 70 kDa
    Cat.:
    E13128h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    ELISA Kit for Mouse U1 snRNP 70 kDa
    Cat.:
    E13128b
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse U1 snRNP 70 kDa
    Cat.:
    U13128h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse U1 snRNP 70 kDa
    Cat.:
    U13128b
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse U1 snRNP 70 kDa
    Cat.:
    U13128m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Mouse U1 snRNP 70 kDa
    Cat.:
    P13128Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse U1 snRNP 70 kDa
    Polyclonal Antibody for Mouse U1 snRNP 70 kDa
    Cat.:
    P13128Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Mouse U1 snRNP 70 kDa
    Monoclonal Antibody for Mouse U1 snRNP 70 kDa
    Monoclonal Antibody for Mouse U1 snRNP 70 kDa
    Protein for Mouse U1 snRNP 70 kDa
    Protein for Mouse U1 snRNP 70 kDa
    Protein for Mouse U1 snRNP 70 kDa

    R&D Technical Data
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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "The transcriptional landscape of the mammalian genome."
      Carninci P. , Kasukawa T. , Katayama S. , Gough J. , Frith M.C. , Maeda N. , Oyama R. , Ravasi T. , Lenhard B. , Wells C. , Kodzius R. , Shimokawa K. , Bajic V.B. , Brenner S.E. , Batalov S. , Forrest A.R. , Zavolan M. , Davis M.J. , more...
      Science309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
      strain: C57BL/6J.
      tissue: Kidney.
      tissue: Testis.
    2. 2.
      "Analysis of genomic clones of the murine U1RNA-associated 70-kDa protein reveals a high evolutionary conservation of the protein between human and mouse."
      Hornig H. , Fischer U. , Costas M. , Rauh A. , Luehrmann R.
      Eur. J. Biochem.182:45-50(1989) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 71-448 (ISOFORMS 1 AND 2)
      strain: BALB/c.
    3. 3.
      "Phosphoproteomic analysis of the developing mouse brain."
      Ballif B.A. , Villen J. , Beausoleil S.A. , Schwartz D. , Gygi S.P.
      Mol. Cell. Proteomics3:1093-1101(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-408;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Embryonic brain.
    4. 4.
      "Evidence for a direct role of the disease modifier SCNM1 in splicing."
      Howell V.M. , Jones J.M. , Bergren S.K. , Li L. , Billi A.C. , Avenarius M.R. , Meisler M.H.
      Hum. Mol. Genet.16:2506-2516(2007) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH SCNM1;SUBCELLULAR LOCATION
    5. 5.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-408 AND SER-419;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Liver.
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